Listing description
Borage seed oil has
one of the highest amounts of γ-linolenic acid (GLA) of seed oils —
higher than blackcurrant seed oil or evening primrose oil, to which it is considered similar. GLA typically comprises
about 24% of the oil.
Detailed description
Effects
GLA is converted to dihomo-γ-linolenic
acid (DGLA), a
precursor to a variety of the 1-series prostaglandins and the 3-series leukotrienes. It inhibits leukotriene
synthesis to provide therapy in rheumatologic illness. Borage seed oil may
therefore have anti-inflammatory and anti-thrombotic effects and it has
been studied for its potential to treat inflammatory disorders, arthritis, atopic eczema, and respiratory
inflammation.
Uses
In herbal medicine, borage seed oil
has been used for skin disorders such as eczema, seborrheic dermatitis,
and neurodermatitis; it has also been used for rheumatoid arthritis,stress, premenstrual syndrome, diabetes, attention
deficit-hyperactivity disorder (ADHD), acute respiratory
distress syndrome (ARDS), alcoholism, pain and swelling
(inflammation), and for
preventing heart disease and stroke.[2] There is insufficient
scientific evidence to determine the effectiveness of borage for a majority of
these uses.
Several clinical
studies have shown it to be ineffective at treating atopic eczema. Its efficacy to
treat eczema was not better than placebo.
Safety
Adverse effects
Borage oil may
contain the pyrrolizidine
alkaloid amabiline, which is hepatotoxic leading
to a risk of liver damage. Patients
should use borage oil certified free of toxic unsaturated pyrrolizidine
alkaloids (UPAs).[1] Consumption of 1-2 g
of borage seed oil daily can result in an intake of toxic UPAs approaching 10
ug.[1] The German Federal
Health Agency specifies consumption to be limited to 1 ug of UPA daily.[1]
Borage oil may be
unsafe during pregnancy because preliminary studies suggest borage oil has a teratogenic effect and that its prostaglandin E agonist
action may cause premature labor.[1][9]
Seizures have been
reported as a complication of ingestion of borage oil in doses of 1,500 to
3,000 mg daily,[10] although
a mixed review of borage oil's effect on seizure thresholds indicates that borage
oil quality varies.[11] A specific
extraction process may offer purified products with 50%+ GLA content.
Borage seed oil
might prolong bleeding time, increase the risk of bruising and bleeding, and
increase the risk of bleeding during and after surgery.[2]
Interactions
Because borage oil
can theoretically lower the seizure threshold due to its GLA content, it could
therefore trigger a seizure in users of phenothiazines or tricyclic
antidepressants.
Use of NSAIDs with borage oil may
theoretically decrease the effects of borage oil, as NSAIDs interfere with the
synthesis of prostaglandin E.
PRICE
$449.69/KG OR $204.40/IB
For more information:
mobile: +2348039721941
contact person: emeaba uche
e-mail: emeabau@yahoo.com
website: www.franchiseminerals.com
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